DETECT— Navigating a New Era in Alzheimer’s Disease: Integrating Disease-Modifying Therapies into Clinical Practice

FACULTY

Marwan Noel Sabbagh, MD, FAAN, FANA
Moreno Family Chair for Alzheimer's Research
Vice Chairman for Research and Professor
Department of Neurology
Barrow Neurological Institute
Phoenix, AZ

Neil Skolnik, MD
Professor of Family and Community Medicine
Sidney Kimmel Medical College
Thomas Jefferson University
Associate Director, Family Medicine Residency Program
Abington Jefferson Health
Abington, PA

PROGRAM OVERVIEW

In this enduring grand rounds program, we will provide instruction on screening, diagnosing, and staging of mild cognitive impairment and Alzheimer's disease. The lecture and case-based scenarios will educate on the appropriate use of disease-modifying therapy, assessing and managing adverse events associated with these therapies, and implementing tools to solve issues with access to therapy. Finally, the faculty will discuss shared decision making and multidisciplinary teams as essential elements for successful care of these patients.

TARGET AUDIENCE

This activity is designed to meet the educational needs of health care providers involved in the diagnosis and continued care of patients with Alzheimer's disease, including primary care physicians, neurologists, geriatricians, psychiatrists, nurses, NPs, PAs, and other multidisciplinary team members.

LEARNING OBJECTIVES

  • Integrate evidence-based pathways for screening, diagnosing, and staging MCI and AD
  • Appraise clinical practice recommendations informing use of DMTs for AD and identifying those who qualify for treatment based on available clinical data
  • Assess and manage potential adverse events associated with DMTs for AD using a multidisciplinary approach
  • Develop practice protocols to improve access to DMTs for AD
  • Apply best practices for shared decision making when discussing DMT treatment for AD, including discussions of treatment benefits, risks, and what to expect with therapy

JOINT ACCREDITATION STATEMENT

In support of improving patient care, Med Learning Group is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

PHYSICIAN CREDIT DESIGNATION STATEMENT

Med Learning Group designates this enduring activity for a maximum of 1.0 AMA PRA Category 1 CreditTM. Physicians should claim only the credit commensurate with the extent of their participation in the enduring activity.

NURSES (ANCC) CREDIT DESIGNATION

Med Learning Group designates this activity for a maximum of 1.0 ANCC contact hour.

PHARMACISTS AND PHARMACY TECHNICIANS (ACPE) CREDIT DESIGNATION

Med Learning Group designates this activity for a maximum of up to 1.0 knowledge-based CPE contact hours.

ASWB Credit Designation Statement for Jointly Accredited Organizations (Social Worker Credit)

As a Jointly Accredited Organization, Med Learning Group is approved to offer social work continuing education by the Association of Social Work Boards (ASWB) Approved Continuing Education (ACE) program. Organizations, not individual courses, are approved under this program. Regulatory boards are the final authority on courses accepted for continuing education credit.

Social workers completing this course receive 1.0 asynchronous continuing education credit.

AAPA Credit Designation Statement -- Enduring Materials

Med Learning Group has been authorized by the American Academy of Physician Associates (AAPA) to award AAPA Category 1 CME credit for activities planned in accordance with AAPA CME Criteria. This activity is designated for 1.0 AAPA Category 1 CME credit. Approval is valid until May 15, 2026. PAs should only claim credit commensurate with the extent of their participation.


Interprofessional Continuing Education (IPCE) Credit Designation Statement

This activity was planned by and for the healthcare team, and learners will receive 1.0 Interprofessional Continuing Education (IPCE) credits for learning and change.


NOTE to Pharmacists:
The only official Statement of Credit is the one you pull from CPE Monitor. You must request your certificate within 45 days of your participation in the activity to meet the deadline for submission to CPE Monitor. Credits are generally reported during the first week of each month for those who claimed during the month prior.

DISCLOSURE POLICY STATEMENT

In accordance with the Accreditation Council for Continuing Medical Education (ACCME) Standards for Integrity and Independence in Accredited Continuing Education, educational programs sponsored by Med Learning Group must demonstrate balance, independence, objectivity, and scientific rigor. All faculty, authors, editors, staff, and planning committee members participating in an MLG-sponsored activity are required to disclose any relevant financial interest or other relationship with the manufacturer(s) of any commercial product(s) and/or provider(s) of commercial services that are discussed in an educational activity.

DISCLOSURE OF RELEVANT FINANCIAL RELATIONSHIPS

Speaker Relationships Manufacturer
Marwan Noel Sabbagh, MD Consultant Lilly, Anavex Life Sciences, Eisai, Signant Health, GlaxoSmithKline, Sanofi, NetraMark, Alzheon, Athira Pharma, NeuroTherapia
Board of Directors CervoMed
Neil Skolnik, MD Consultant AstraZeneca, Teva, Lilly, Sanofi, Sanofi Pasteur, GlaxoSmithKline, Bayer, Abbott, Novo Nordisk
Speakers Bureau AstraZeneca, Lilly, GlaxoSmithKline, Teva, Bayer, Heartland
Contracted research AstraZeneca, GlaxoSmithKline, Novo Nordisk, Novartis

All relevant financial relationships have been mitigated.

Content Review

The content of this activity was independently peer-reviewed by a physician and nurse reviewer.

Content Review

The content of this activity was independently peer reviewed by a physician and nurse reviewer.

Individuals in Control of the Content of the Activity

The individuals in control of the content of this activity have reported the following financial relationships or relationships to products or devices they have with ineligible companies related to the content of this CE activity:

  • Matthew Frese, MBA, CEO of Med Learning Group, has nothing to disclose.
  • Lauren Welch, MA, Sr VP of Operations for Med Learning Group, has nothing to disclose.
  • Sharine Griggs, Senior Program Manager for Med Learning Group, has nothing to disclose.
  • Dominique Barton, B.S. BSN, Nursing Reviewer, has nothing to disclose.
  • A medical reviewer from CME Peer Review LLC, has nothing to disclose.
  • Chris Drury, Medical Director for Med Learning Group, has nothing to disclose.
  • Daniel Dasilva, Accreditation and Outcomes Coordinator for Med Learning Group, has nothing to disclose.
  • Emmanuella Foucault, Associate Program Manager for Med Learning Group, has nothing to disclose.

DISCLOSURE OF UNLABELED USE

Med Learning Group requires that faculty participating in any CE activity disclose to the audience when discussing any unlabeled or investigational use of any commercial product or device not yet approved for use in the United States. During this lecture, the faculty may mention the use of medications for both FDA-approved and non-approved indications.

METHOD OF PARTICIPATION

There are no fees for participating and receiving CE credit for this activity. In order to obtain your certificate for the mentioned accreditation, participants need to successfully complete the associated pre/post activities and evaluation. Your certificate will be provided as a downloadable file.

DISCLAIMER

Med Learning Group makes every effort to develop CE activities that are science based. This activity is designed for educational purposes. Participants have a responsibility to use this information to enhance their professional development in an effort to improve patient outcomes. Conclusions drawn by the participants should be derived from careful consideration of all available scientific information. The participant should use his/her clinical judgment, knowledge, experience, and diagnostic decision-making expertise before applying any information, whether provided here or by others, for any professional use.

For CE questions, please contact Med Learning Group at [email protected]

Contact this CE provider at Med Learning Group for privacy and confidentiality policy statement information at www.medlearninggroup.com/privacy-policy/

AMERICANS WITH DISABILITIES ACT

Event staff will be glad to assist you with any special needs (eg, physical, dietary, etc). Please contact Med Learning Group prior to participating at [email protected]

RELEASED DATE: May 15, 2025
EXPIRATION DATE: May 15, 2026

Copyright © 2025 Med Learning Group. All rights reserved. These materials may be used for personal use only. Any rebroadcast, distribution, or reuse of this presentation or any part of it in any form for other than personal use without the express written permission of Med Learning Group is prohibited.

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Scientific Council

Marc Agronin, MD

Chief Medical Officer
Frank C. and Lynn Scaduto MIND Institute and Behavioral Health
Miami Jewish Health
Miami, FL

Liana G. Apostolova, MD, MSc, FAAN

Associate Dean of Alzheimer’s Disease Research
Indiana University Distinguished Professor
Barbara and Peer Baekgaard Professor of Alzheimer's Disease Research
Professor in Neurology, Radiology, Medical and Molecular Genetics
Indiana University School of Medicine
Department of Neurology
Indianapolis, IN

Alireza Atri, MD, PhD

Chief Medical Officer, Banner Research
Banner Alzheimer’s and Research Institutes
Pheonix, Sun City, and Tucson, AZ
Director, Banner Sun Health Research Institute
Sun City, AZ

Frederik Barkhof, MD, PhD, FRCR

Professor of Neuroradiology
Department of Radiology and Nuclear Medicine
Amsterdam UMC (location VU mc)
Amsterdam, The Netherlands
UCL Queen Square Institute of Neurology
UCL Hawkes Institute
London, United Kingdom

Sharon A. Brangman, MD, FACP, AGSF

Distinguished Service Professor
Chair, Department of Geriatrics
Director, Upstate Center of Excellence for Alzheimer’s Disease
SUNY Upstate Medical University
Syracuse, New York

Christopher Chen, BM BCh, MRCP, FAMS, FRCP

Professor, Department of Pharmacology
Director, Memory Aging and Cognition Centre
Yong Loo Lin School of Medicine
National University of Singapore
Singapore

Choong Chih Ching, MBChb NZ, FRCR UK

Senior Consultant, Department of Diagnostic Imaging
RadLink, Singapore
Visiting Consultant, National University Hospital and National Cancer Centre of Singapore

Anupama Roy Chowdhury, MBBS, MRCP, FAMS

Head and Senior Consultant
Department of Geriatric Medicine
Singapore General Hospital
Singapore

Natalie Christian, MD

Assistant Professor, Geriatrics
Program Director, Geriatric Medicine Fellowship
Tulane University School of Medicine
Southeast Louisiana Veterans Healthcare System
New Orleans, LA

Petrice M. Cogswell, MD, PhD

Associate Professor
Mayo Clinic
Rochester, Minnesota

Ariel F. Cole, MD, FAAFP

Program Director, AdventHealth Geriatric Fellowship
Winter Park, FL

Brad Dickerson, MD, MMSc, FAAN, FANPA

Professor of Neurology, Harvard Medical School
Director, Frontotemporal Disorders Unit, Department of Neurology, Massachusetts General Hospital
Boston, MA

Richard M. Dupee, MD, MACP, AGSF

Clinical Professor of Medicine
Tufts University School of Medicine
Clinical professor, Department of Public Health and Community Medicine, Tufts University
Chief, Geriatrics Service, Tufts Medical Center
Senior Physician, Pratt Diagnostic Center
Dean ex officio, Office of International Affairs, Tufts University School of Medicine
Boston, MA

Fanny Elahi, MD, PhD

Associate Professor of Neurology, Neuroscience, and AI and Human Health
Icahn School of Medicine
Mount Sinai
New York, NY

James M. Ellison, MD, MPH

Professor of Psychiatry and Human Behavior
Sidney Kimmel Medical College
Co-Director, Comprehensive Alzheimer’s Center
Vickie & Jack Farber Institute for Neuroscience
Thomas Jefferson University
Philadelphia, PA

Juan Fortea, MD, PhD

Professor of Neurology
Director, Alzheimer-Down Unit
Hospital de la Santa Creu i Sant Pau
Sant Pau Biomedical Research Institute
Barcelona, Spain

Ana M. Franceschi, MD, PhD

Associate Professor of Radiology
Director of Dementia Imaging
Director of Molecular Neuroimaging
Donald and Barbara Zucker School of Medicine at Hofstra/Northwell
Lenox Hill Hospital
New York, New York

Giovanni B. Frisoni, MD

Professor of Clinical Neuroscience
University of Geneva
Director, Memory Clinic
Geneva University Hospitals
Geneva, Switzerland

Samuel Gandy, MD. PhD

Professor of Neurology & Psychiatry
Icahn School of Medicine at Mount Sinai
James J Peters VA Medical Center
New York, New York

James E. Galvin, MD, MPH

Professor of Neurology
University of Miami Miller School of Medicine
Miami, FL

David S. Geldmacher, MD

Professor and Director
Division of Memory Disorders and Behavioral Neurology
Department of Neurology
Heersink School of Medicine
University of Alabama at Birmingham
Birmingham, AL

George T. Grossberg, MD

Henry & Amelia Nasrallah Endowed Professor
Director of Geriatric Psychiatry
Department of Psychiatry & Behavioral Neuroscience
Saint Louis University School of Medicine
St. Louis, MO

M. Atsushi Iwata, MD, PhD

Professor of Neurology
Department of Neurology
The University of Tokyo
Tokyo, Japan

Scott A. Kaiser, MD

Director of Geriatric Cognitive Health
Pacific Neuroscience Institute
Santa Monica, CA
Adjunct Professor
USC Leonard Davis School of Gerontology
Los Angeles, CA

Lynn E. Kassel, PharmD, BCPS

Associate Professor of Pharmacy Practice
Drake University College of Pharmacy & Health Sciences
Des Moines, IA

Diana R. Kerwin, MD, CPI

President, Kerwin Medical Center
Chief, Geriatric Medicine, Texas Health Presbyterian Hospital
Dallas, TX

Alka Khera, MD

Assistant Professor
UT Southwestern Neurology
Dallas, TX

Sumeet Kumar, MBBS, DNB, FRCR, EDiNR

Senior Consultant, Department of Neuroradiology
National Neuroscience Institute of Singapore
Clinical Assistant Professor, Duke-NUS Medical School
Adjunct Director for Advanced Magnetic Resonance Imaging Research
Radiological Sciences Academic Clinical Program (RADSC ACP)
SingHealth Duke-NUS Academic Medical Centre
Singapore

Rosemary D. Laird, MD, MHSA, AGSF

Chief Medical Officer, My Memory Clinic
Principal Investigator, ClinCloud Clinical Trials
Viera, Florida

Chi-Ying (Roy) Lin, MD, MPH, FAAN

Director, CurePSP Center of Care for PSP, CBD, and MSA
Assistant Professor of Neurology
Alzheimer's and Parkinson's Disease Centers
Baylor College of Medicine
Houston, TX

Catherine A. Madison, MD

Founding Director Ray Dolby Brain Health Center
San Francisco, CA

Scott McGinnis, MD

Assistant Professor of Neurology, Harvard Medical School
Center for Alzheimer Research and Treatment
Brigham and Women's Hospital
Frontotemporal Disorders Unit
Massachusetts General Hospital
Boston, MA

Kristin S. Meyer, PharmD, BCGP, FASCP

Professor of Pharmacy Practice
Drake University College of Pharmacy and Health Sciences
Des Moines, IA

Charles Montano, MD

Owner, Principal Investigator
CT Clinical Research
Cromwell, CT

Mary Norman, MD

Geriatrician
Cedars-Sinai Medical Group
Los Angeles, CA

Tiago Gil Oliveira, MD, PhD

Associate Professor
Life and Health Sciences Research Institute
School of Medicine
University of Minho
Neuroradiologist
Hospital de Braga
Braga, Portugal

Monica Parker, MD

Associate Professor of Neurology
Lead, Outreach, Recruitment, and Engagement Core
Goizueta Alzheimer's Disease Research Center
Goizueta Brain Health Institute
Emory University
Atlanta, Georgia

Lucilla Parnetti, MD

Professor of Neurology
Department of Medicine and Surgery
University of Perugia
Perugia, Italy

Manisha Parulekar, MD, FACP, AGSF, CMD

Director, Division of Geriatrics
Co-director, Center for Memory Loss and Brain Health
Hackensack University Medical Center
Hackensack, NJ

Giulio Maria Pasinetti, MD, PhD

The Saunders Family Chair in Neurology, Professor in Neurology
Director, Mount Sinai Center in Advance Botanical Research in Molecular Integrative Neuroresilience
Icahn School of Medicine at Mount Sinai
New York, NY
Director, Basic and Biomedical Research and Training Program, Geriatric Research and Clinical Center
James J. Peters Department of Veterans Affairs Medical Center
Bronx, NY

Robert Perneczky, MD, PhD 

Professor of Psychiatry
Department of Psychiatry and Psychotherapy
Ludwig-Maximilians-University Munich
German Center for Neurodegenerative Diseases
Munich, Germany

Anton P. Porsteinsson, MD

William B. and Sheila Konar Professor of Psychiatry, Neurology,
Neuroscience, and Medicine
Director, Alzheimer’s Disease Care, Research and Education
Program (AD CARE)
University of Rochester School of Medicine and Dentistry
Rochester, NY

Michael S. Rafii, MD, PhD

Professor of Clinical Neurology
Medical Director, Alzheimer’s Therapeutic Research Institute
Keck School of Medicine of USC
Los Angeles, California, USA

William D. Rhoades, DO, FACP

Chief Medical Officer
Advocate Good Samaritan Hospital
Downers Grove, IL

Barry W. Rovner, MD

Professor, Departments of Psychiatry & Neurology
Sidney Kimmel Medical College
Thomas Jefferson University
Philadelphia, PA

Marwan Noel Sabbagh, MD, FAAN, FANA

Moreno Family Chair for Alzheimer’s Research
Vice Chairman for Research and Professor
Department of Neurology
Barrow Neurological Institute
Phoenix, AZ

Martin J. Sadowski, MD, PhD

Zachary and Elizabeth M. Fisher Professor of Neurodegeneration and Alzheimer's Disease
Professor of Neurology, Psychiatry, and Biochemistry & Molecular Pharmacology
New York University Grossman School of Medicine Director, Fisher Center Alzheimer’s Clinical Trials Program
New York, NY

Stephen Salloway, MD, MS

Professor, Psychiatry and Human Behavior
Professor of Neurology, Alpert Medical School of Brown University
Providence, Rhode Island

Angela Sanford, MD, CMD

Associate Professor of Internal Medicine-Geriatrics
Saint Louis University School of Medicine
Ballwin, MO

Philip Scheltens, MD, PhD

Professor Emeritus of Neurology
Amsterdam University Medical Center
Head Dementia Fund at EQT Life Sciences
Amsterdam, Netherlands

Suzanne E. Schindler, MD, PhD

Associate Professor of Neurology
Division of Neurology
Washington University School of Medicine in St. Louis
Investigator, Knight Alzheimer Disease Research Center
St. Louis, Missouri, USA

Paul E. Schulz, MD

Rick McCord Professor of Neurology
Umphrey Family Professor of Neurodegenerative Disorders
Director, Memory Disorders and Dementia Clinic
UTHealth Houston
Houston, TX

Sharon J. Sha, MD, MS

Clinical Professor
Clinical Professor Neurology and Neurological Sciences Stanford University Chief, Stanford Memory Disorders Center Stanford Medicine Health Care
Palo Alto, CA

Jiong Shi, MD

Professor of Neurology
Department of Neurology
Huashan Hospital
Fudan University
Shanghai, China

Neil Skolnik, MD

Professor of Family and Community Medicine
Sidney Kimmel Medical College
Thomas Jefferson University
Philadelphia, PA

Sandra Swantek, MD

Director, Section of Geriatric Psychiatry
RUSH University Medical Center
Chicago, IL

R. Scott Turner, PhD, MD

Professor of Neurology
Director of the Memory Disorders Program
Georgetown University
Washington, DC

Lawren VandeVrede, MD, PhD

Assistant Professor of Neurology
Memory and Aging Center
Department of Neurology
University of California, San Francisco
San Francisco, California, USA

Chuck Vega, MD, FAAFP

Health Sciences Clinical Professor
UC Irvine Department of Family Medicine
Director, UCI Program in Medical Education for the Latino Community
University of California Irvine
Irvine, CA

Nicolas Villain, MD, PhD

Professor of Neurology
Department of Neurology
Sorbonne University
Neurologist, Pitié-Salpêtrière Hospital
Assistance Publique – Hôpitaux de Paris
Paris, France

Geoffrey C. Wall, PharmD, FCCP, BCPS

John R. Ellis Distinguished Chair of Pharmacy Practice
Professor of Clinical Sciences
Director, Drake Drug Information Center
Drake University College of Pharmacy and Health Sciences
Internal Medicine Clinical Pharmacist
Iowa Methodist Medical Center
Des Moines, IA

David A. Wolk, MD, FAAN

Professor of Neurology
Director, Penn Alzheimer’s Disease Research Center
University of Pennsylvania
Philadelphia, PA