{"id":209514,"date":"2022-12-13T09:59:33","date_gmt":"2022-12-13T14:59:33","guid":{"rendered":"https:\/\/detectalz.com\/diagnostico-y-evaluacion-de-la-enfermedad-de-alzheimer\/"},"modified":"2024-03-15T19:27:45","modified_gmt":"2024-03-15T23:27:45","slug":"diagnostico-y-evaluacion-de-la-enfermedad-de-alzheimer","status":"publish","type":"page","link":"https:\/\/detectalz.com\/es\/diagnostico-y-evaluacion-de-la-enfermedad-de-alzheimer\/","title":{"rendered":"Diagn\u00f3stico y Evaluaci\u00f3n de la Enfermedad de Alzheimer"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"209514\" class=\"elementor elementor-209514 elementor-209208\" data-elementor-post-type=\"page\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-23deb6c insidepage-bg elementor-section-full_width elementor-section-height-default elementor-section-height-default\" data-id=\"23deb6c\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;video&quot;,&quot;background_play_on_mobile&quot;:&quot;yes&quot;,&quot;background_video_link&quot;:&quot;https:\\\/\\\/detectalz.com\\\/wp-content\\\/uploads\\\/2022\\\/11\\\/Detect-Animated-Video-Background-Provider-Toolkit-221116.mp4&quot;}\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-background-video-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<video class=\"elementor-background-video-hosted\" role=\"presentation\" autoplay muted playsinline loop><\/video>\n\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-background-overlay\"><\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-no\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-c115010\" data-id=\"c115010\" data-element_type=\"column\" data-e-type=\"column\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-187ae66 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"187ae66\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;video&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-1aa29ad\" data-id=\"1aa29ad\" data-element_type=\"column\" data-e-type=\"column\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-3ba5eea video-container elementor-widget elementor-widget-html\" data-id=\"3ba5eea\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"html.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<video width=\"100%\" height=\"300\" autoplay=\"\" loop=\"\" muted=\"\" playsinline=\"\">\n<source src=\"https:\/\/detectalz.com\/wp-content\/uploads\/2022\/12\/Diagnosis-and-Assesing-AD.mp4\" type=\"video\/mp4; codecs=\"hvc1\"\">\n<source src=\"https:\/\/detectalz.com\/wp-content\/uploads\/2022\/12\/Diagnosis-and-Assesing-AD.webm\" type=\"video\/webm\">\n<\/source><\/source><\/video>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-f02db92 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"f02db92\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-3d0a946\" data-id=\"3d0a946\" data-element_type=\"column\" data-e-type=\"column\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-3dbfe7c elementor-widget elementor-widget-text-editor\" data-id=\"3dbfe7c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>La enfermedad de Alzheimer (EA) es una afecci\u00f3n neurodegenerativa, caracterizada por la acumulaci\u00f3n de prote\u00edna beta-amiloide extraneuronal (placas) y prote\u00edna tau intraneuronal (ovillos) en el cerebro.<sup>1<\/sup> Las etapas de la EA se clasifican por el grado de deterioro cognitivo, que va desde ning\u00fan s\u00edntoma de EA en la forma precl\u00ednica hasta s\u00edntomas graves en etapas posteriores.<sup>1,2<\/sup><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-7701614 elementor-widget elementor-widget-image\" data-id=\"7701614\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"636\" height=\"429\" src=\"https:\/\/detectalz.com\/wp-content\/uploads\/2024\/03\/Stages-Within-the-AD-Continuum.png\" class=\"attachment-large size-large wp-image-210318\" alt=\"\" srcset=\"https:\/\/detectalz.com\/wp-content\/uploads\/2024\/03\/Stages-Within-the-AD-Continuum.png 636w, https:\/\/detectalz.com\/wp-content\/uploads\/2024\/03\/Stages-Within-the-AD-Continuum-300x202.png 300w\" sizes=\"(max-width: 636px) 100vw, 636px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-baab1c0 elementor-widget elementor-widget-heading\" data-id=\"baab1c0\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Reconocimiento de los S\u00edntomas de la Enfermedad de Alzheimer <\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-95453e5 elementor-widget elementor-widget-text-editor\" data-id=\"95453e5\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Uno de los s\u00edntomas m\u00e1s tempranos y comunes de la EA es la p\u00e9rdida de memoria, espec\u00edficamente la alteraci\u00f3n de la memoria &#8220;reciente&#8221; con un relativo respeto de la memoria a largo plazo.<sup>2,4<\/sup> Los pacientes con EA eventualmente pueden desarrollar dificultades con la resoluci\u00f3n de problemas, el juicio, la organizaci\u00f3n y la function ejecutiva, y posteriormente una disminuci\u00f3n en la capacidad de realizar varias tareas y pensamiento abstracto.<sup>2<\/sup> Con la progresi\u00f3n de la enfermedad surge la incapacidad para completar tareas y una reducci\u00f3n en la percepci\u00f3n, lo que potencialmente afecta la capacidad para realizar actividades como conducir de manera segura.<sup>4<\/sup><\/p><p>En etapas posteriores, surgen trastornos del lenguaje y problemas con las habilidades visuoespaciales.<sup>2<\/sup> Las etapas moderadas a tard\u00edas de la EA tambi\u00e9n pueden demostrar s\u00edntomas neuropsiqui\u00e1tricos de apat\u00eda, falta de inhibici\u00f3n, psicosis, agitaci\u00f3n, retraimiento social y deambulaci\u00f3n, y est\u00e1n asociados con un declive m\u00e1s r\u00e1pido si est\u00e1n presentes tempranamente.<sup>2,4<\/sup> En la etapa final de la EA, las dificultades con la comunicaci\u00f3n verbal y el movimiento pueden resultar en estar postrado en cama e incontinencia, con una dependencia total de los cuidadores.<sup>1,2<\/sup><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1d5d9b4 elementor-widget elementor-widget-image\" data-id=\"1d5d9b4\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"636\" height=\"827\" src=\"https:\/\/detectalz.com\/wp-content\/uploads\/2024\/03\/CL_Overview-of-AD-Symptoms-by-Stage_1-2-5_v1.png\" class=\"attachment-large size-large wp-image-210320\" alt=\"\" srcset=\"https:\/\/detectalz.com\/wp-content\/uploads\/2024\/03\/CL_Overview-of-AD-Symptoms-by-Stage_1-2-5_v1.png 636w, https:\/\/detectalz.com\/wp-content\/uploads\/2024\/03\/CL_Overview-of-AD-Symptoms-by-Stage_1-2-5_v1-231x300.png 231w\" sizes=\"(max-width: 636px) 100vw, 636px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-666c352 elementor-widget elementor-widget-heading\" data-id=\"666c352\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Realizar el Diagn\u00f3stico de la Enfermedad de Alzheimer<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3df2961 elementor-widget elementor-widget-text-editor\" data-id=\"3df2961\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Dado que la EA generalmente empeora con el tiempo, el diagn\u00f3stico precoz beneficia tanto a los pacientes como a sus cuidadores.<sup>2<\/sup> Les permite abordar los factores de riesgo modificables que pueden retrasar el deterioro cognitivo, comenzar el tratamiento o inscribirse en ensayos cl\u00ednicos antes de que se hayan establecido las etapas graves, y potencialmente preservar el funcionamiento diario por m\u00e1s tiempo.<sup>1<\/sup> El diagnostic precoz de la EA tambi\u00e9n brinda a los pacientes y cuidadores tiempo adicional para aprender a manejar los s\u00edntomas conductuales, discutir la planificaci\u00f3n futura y los problemas personales\/financieros, abordar las preocupaciones de seguridad y establecer una red de apoyo.<sup>1<\/sup><\/p><p>El diagn\u00f3stico de la EA comienza obteniendo una historia precisa, especialmente de familiares y cuidadores.<sup>2<\/sup> Un examen f\u00edsico completo, incluidos los hallazgos neurol\u00f3gicos, ayuda a descartar otras posibles causas de demencia.<sup>2<\/sup> Estudios recientes sugieren que la anosmia puede ser un marcador temprano de la EA, pero se necesita m\u00e1s investigaci\u00f3n y esto no es un hallazgo diagn\u00f3stico ampliamente utilizado.<sup>6<\/sup><\/p><p>La evaluaci\u00f3n cognitiva, neurol\u00f3gica y psicol\u00f3gica detallada puede proporcionar mucha informaci\u00f3n sobre la preservaci\u00f3n o p\u00e9rdida de la funci\u00f3n independiente, as\u00ed como la presencia\/tipos de s\u00edntomas neuropsiqui\u00e1tricos.<sup>4<\/sup> Los ex\u00e1menes del estado mental, especialmente aquellos que eval\u00faan la concentraci\u00f3n, la atenci\u00f3n, la memoria, el lenguaje, la praxis y las funciones ejecutivas visoespaciales, pueden ayudar a documentar la presencia y etapa de la demencia.<sup>2,4<\/sup> Adem\u00e1s, las pruebas neuropsicol\u00f3gicas formales y las evaluaciones cognitivas no solo pueden establecer una l\u00ednea de base de demencia, sino tambi\u00e9n ayudar a distinguir entre otras formas de demencia (pseudodemencia, demencia con cuerpos de Lewy, demencia vascular y degeneraci\u00f3n lobular frontotemporal) as\u00ed como evaluar competencias para realizer tareas potencialmente peligrosas.<sup>4<\/sup> Las pruebas neuropsicol\u00f3gicas tambi\u00e9n son el m\u00e9todo m\u00e1s confiable para detectar el DCL.<sup>2<\/sup> Haga clic aqu\u00ed para ver y descargar un kit de evaluaci\u00f3n cognitiva proporcionado por la Asociaci\u00f3n de Alzheimer<sup>\u00ae<\/sup>.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4ba47ad elementor-widget elementor-widget-image\" data-id=\"4ba47ad\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"636\" height=\"274\" src=\"https:\/\/detectalz.com\/wp-content\/uploads\/2022\/11\/CL_Molecular-and-Topographic-Biomarkers-in-AD_v1.jpg\" class=\"attachment-large size-large wp-image-209248\" alt=\"\" srcset=\"https:\/\/detectalz.com\/wp-content\/uploads\/2022\/11\/CL_Molecular-and-Topographic-Biomarkers-in-AD_v1.jpg 636w, https:\/\/detectalz.com\/wp-content\/uploads\/2022\/11\/CL_Molecular-and-Topographic-Biomarkers-in-AD_v1-300x129.jpg 300w, https:\/\/detectalz.com\/wp-content\/uploads\/2022\/11\/CL_Molecular-and-Topographic-Biomarkers-in-AD_v1-50x22.jpg 50w\" sizes=\"(max-width: 636px) 100vw, 636px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5e4216c elementor-widget elementor-widget-text-editor\" data-id=\"5e4216c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Aunque a\u00fan no se recomiendan para uso diagn\u00f3stico de rutina, se est\u00e1n investigando varios biomarcadores serol\u00f3gicos, plasm\u00e1ticos e de im\u00e1genes avanzadas para ayudar a respaldar un diagn\u00f3stico de EA.<sup>4,7<\/sup> Los biomarcadores moleculares identifican dep\u00f3sitos de prote\u00ednas espec\u00edficas en el cerebro, como el amiloide encontrado en placas de amiloide o las prote\u00ednas tau encontradas en ovillos neurofibrilares.<sup>4<\/sup> Los biomarcadores topogr\u00e1ficos (neurodegenerativos) ayudan a localizar cambios patol\u00f3gicos regionals en el cerebro asociados con la EA.<sup>3<\/sup> La neuroimagen, incluida la resonancia magn\u00e9tica (RM) y la imagen cerebral funcional (por ejemplo, PET de amiloide\/tau y tomograf\u00eda computarizada por emisi\u00f3n de fot\u00f3n \u00fanico [SPECT]), tambi\u00e9n puede ayudar a descartar otras posibles causas de demencia.<sup>2,4<\/sup> M\u00e1s recientemente, se ha centrado la atenci\u00f3n en pTau217, es decir, la tau fosforilada en el amino\u00e1cido 217, ya que este biomarcador ha demostrado consistentemente un alto rendimiento en la diferenciaci\u00f3n de la EA de otros trastornos neurodegenerativos y en la detecci\u00f3n de patolog\u00eda de EA en pacientes con DCL.<sup>8<\/sup><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-554fdc9 elementor-widget elementor-widget-image\" data-id=\"554fdc9\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"636\" height=\"604\" src=\"https:\/\/detectalz.com\/wp-content\/uploads\/2024\/03\/CL_Distinguishing-PET-and-MRI-scans-1.jpg\" class=\"attachment-large size-large wp-image-210327\" alt=\"\" srcset=\"https:\/\/detectalz.com\/wp-content\/uploads\/2024\/03\/CL_Distinguishing-PET-and-MRI-scans-1.jpg 636w, https:\/\/detectalz.com\/wp-content\/uploads\/2024\/03\/CL_Distinguishing-PET-and-MRI-scans-1-300x285.jpg 300w\" sizes=\"(max-width: 636px) 100vw, 636px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-7d78453 elementor-widget elementor-widget-text-editor\" data-id=\"7d78453\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Datos recientes de estudios longitudinales han comparado los cambios relacionados con el tiempo en biomarcadores fluidos con la progresi\u00f3n de la enfermedad.<sup>10<\/sup><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3b3b0c7 elementor-widget elementor-widget-image\" data-id=\"3b3b0c7\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"636\" height=\"535\" src=\"https:\/\/detectalz.com\/wp-content\/uploads\/2024\/03\/Schematic-time-course-to-key-AD-biomarkers.png\" class=\"attachment-large size-large wp-image-210322\" alt=\"\" srcset=\"https:\/\/detectalz.com\/wp-content\/uploads\/2024\/03\/Schematic-time-course-to-key-AD-biomarkers.png 636w, https:\/\/detectalz.com\/wp-content\/uploads\/2024\/03\/Schematic-time-course-to-key-AD-biomarkers-300x252.png 300w\" sizes=\"(max-width: 636px) 100vw, 636px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-f5baaee elementor-widget elementor-widget-heading\" data-id=\"f5baaee\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">La Significancia de las Comorbilidades<sup>8<\/sup> para la Enfermedad de Alzheimer<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-db2908d elementor-widget elementor-widget-text-editor\" data-id=\"db2908d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Las comorbilidades m\u00e1s comunes de la EA son la diabetes tipo 2, la enfermedad cardiovascular, la depresi\u00f3n y la enfermedad inflamatoria intestinal. Un factor clave en estas enfermedades cr\u00f3nicas comunes es la presencia de inflamaci\u00f3n. La investigaci\u00f3n est\u00e1 en curso sobre si la inflamaci\u00f3n es una causa o un efecto de la EA; probablemente, tiene una influencia bidireccional en este trastorno neurodegenerativo.<\/p><p>Independientemente, la presencia de estas comorbilidades observadas en pacientes con EA puede tener implicaciones significativas para el tratamiento y el pron\u00f3stico de la EA. Por ejemplo, tanto la diabetes como la depresi\u00f3n est\u00e1n asociadas con un peor pron\u00f3stico en personas con EA. De manera similar, ciertos factores de estilo de vida, como la dieta y el ejercicio, tambi\u00e9n pueden tener un impacto en la funci\u00f3n cognitiva.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-038b2d7 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"038b2d7\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-a5b9dae\" data-id=\"a5b9dae\" data-element_type=\"column\" data-e-type=\"column\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-603bc2f elementor-widget elementor-widget-heading\" data-id=\"603bc2f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Referencias<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4a34793 elementor-widget elementor-widget-text-editor\" data-id=\"4a34793\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<ol><li>Alzheimer\u2019s Association<sup>\u00ae<\/sup>. 2023 Alzheimer\u2019s Disease Facts And Figures. Special report. The patient journey in an era of new treatments. <a href=\"https:\/\/www.alz.org\/media\/Documents\/alzheimers-facts-and-figures.pdf\" target=\"_blank\" rel=\"noopener nofollow external noreferrer\" data-wpel-link=\"external\">https:\/\/www.alz.org\/media\/Documents\/alzheimers-facts-and-figures.pdf<\/a>.<\/li><li>Kumar A, Sidhu J, Goyal A, et al. Alzheimer Disease.\u00a0<em>StatPearls<\/em>. 2022.\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK499922\/\" target=\"_blank\" rel=\"nofollow external noopener noreferrer\" data-wpel-link=\"external\">https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK499922\/<\/a><\/li><li>Porsteinsson AP, Isaacson RS, Knox S, Sabbagh MN, Rubino I. Diagnosis of Early Alzheimer\u2019s Disease: Clinical Practice in 2021. J Prev Alzheimers Dis. 2021;8(3):371-386.<\/li><li>Wolk, DA &amp; Dickerson, BC. Clinical Features and Diagnosis of Alzheimer Disease.\u00a0<em>UpToDate<\/em>.\u00a0<a href=\"https:\/\/www.uptodate.com\/contents\/clinical-features-and-diagnosis-of-alzheimer-disease\" target=\"_blank\" rel=\"nofollow external noopener noreferrer\" data-wpel-link=\"external\">https:\/\/www.uptodate.com\/contents\/clinical-features-and-diagnosis-of-alzheimer-disease<\/a><\/li><li>National Institute on Aging (NIA). What are the Signs of Alzheimer\u2019s Disease.\u00a0<a href=\"https:\/\/www.nia.nih.gov\/health\/what-are-signs-alzheimers-disease\" target=\"_blank\" rel=\"nofollow external noopener noreferrer\" data-wpel-link=\"external\">https:www.nia.nih.gov\/health\/what-are-signs-alzheimers-disease<\/a><\/li><li>Tian Q, Bilgel M, Moghekar AR, Ferrucci L, Resnick SM. Olfaction, Cognitive Impairment, and PET Biomarkers in Community-Dwelling Older Adults<em>. J Alzheimers Dis<\/em>. 2022;86(3):1275-1285.<\/li><li>Alzheimer\u2019s Association<sup>\u00ae<\/sup>. Global biomarker standardization consortium (GBSC).\u00a0<a href=\"https:\/\/www.alz.org\/research\/for_researchers\/partnerships\/gbsc\" target=\"_blank\" rel=\"nofollow external noopener noreferrer\" data-wpel-link=\"external\">https:\/\/www.alz.org\/research\/for_researchers\/partnerships\/gbsc<\/a><\/li><li>Tahami Monfared AA, Phan NTN, Pearson I, et al. A Systematic Review of Clinical Practice Guidelines for Alzheimer\u2019s Disease and Strategies for Future Advancements.\u00a0<em>Neurol Ther<\/em>. 2023;12(4):1257-1284.<\/li><li>Murray ME, Kouri N, Lin WL, et al. Clinicopathologic assessment and imaging of tauopathies in neurodegenerative diseases.\u00a0<em>Alz Res Therapy.\u00a0<\/em>2014;6:1.<\/li><li>Lista S, Santos-Lozano A, Emanuele E, et al. Monitoring synaptic pathology in Alzheimer\u2019s disease through fluid and PET imaging biomarkers: a comprehensive review and future perspectives.\u00a0<em>Mol Psychiatry<\/em>. Published online January 16, 2024.<\/li><li>Santiago JA, Potashkin JA. The Impact of Disease Comorbidities in Alzheimer\u2019s Disease.\u00a0<em>Front Aging Neurosci<\/em>. 2021;13:631770.<\/li><\/ol><p><strong>All URLs accessed on February 14, 2024<\/strong><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-5bfaca5 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"5bfaca5\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-0356b0f\" data-id=\"0356b0f\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-69ff412 elementor-widget elementor-widget-template\" data-id=\"69ff412\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"template.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-template\">\n\t\t\t\t\t<div data-elementor-type=\"page\" data-elementor-id=\"209551\" class=\"elementor elementor-209551 elementor-209550 elementor-209550\" data-elementor-post-type=\"elementor_library\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-4f4140bf elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"4f4140bf\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-4b651090\" data-id=\"4b651090\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-4154e06f elementor-hidden-mobile elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"4154e06f\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-wide\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-inner-column elementor-element elementor-element-b4b3648\" data-id=\"b4b3648\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-9e49bb9 elementor-cta--layout-image-above elementor-cta--valign-middle toolkit-box elementor-cta--skin-classic elementor-animated-content elementor-widget elementor-widget-call-to-action\" data-id=\"9e49bb9\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"call-to-action.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<a class=\"elementor-cta\" href=\"https:\/\/detectalz.com\/el-peso-de-la-enfermedad-de-alzheimer\/?lang=es\">\n\t\t\t\t\t\t\t<div class=\"elementor-cta__content\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-content-item elementor-cta__content-item elementor-cta__image\">\n\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"500\" height=\"403\" src=\"https:\/\/detectalz.com\/wp-content\/uploads\/2024\/03\/The-Burden-of-AD.gif\" class=\"attachment-full size-full wp-image-210343\" alt=\"\" \/>\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t<h2 class=\"elementor-cta__title elementor-cta__content-item elementor-content-item\">\n\t\t\t\t\t\tLa Carga de la EA\t\t\t\t\t<\/h2>\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-inner-column elementor-element elementor-element-65dde0b7\" data-id=\"65dde0b7\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-2cf9d606 elementor-cta--layout-image-above elementor-cta--valign-middle toolkit-box elementor-cta--skin-classic elementor-animated-content elementor-widget elementor-widget-call-to-action\" data-id=\"2cf9d606\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"call-to-action.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<a class=\"elementor-cta\" href=\"https:\/\/detectalz.com\/diagnostico-y-evaluacion-de-la-enfermedad-de-alzheimer\/?lang=es\">\n\t\t\t\t\t\t\t<div class=\"elementor-cta__content\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-content-item elementor-cta__content-item elementor-cta__image\">\n\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"500\" height=\"396\" src=\"https:\/\/detectalz.com\/wp-content\/uploads\/2024\/03\/Diagnosis-and-Assessing-AD.gif\" class=\"attachment-full size-full wp-image-210345\" alt=\"\" \/>\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t<h2 class=\"elementor-cta__title elementor-cta__content-item elementor-content-item\">\n\t\t\t\t\t\tDiagn\u00f3stico y Evaluaci\u00f3n de la Enfermedad de Alzheimer\t\t\t\t\t<\/h2>\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-inner-column elementor-element elementor-element-371791e3\" data-id=\"371791e3\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-276ea98c elementor-cta--layout-image-above elementor-cta--valign-middle toolkit-box elementor-cta--skin-classic elementor-animated-content elementor-widget elementor-widget-call-to-action\" data-id=\"276ea98c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"call-to-action.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<a class=\"elementor-cta\" href=\"https:\/\/detectalz.com\/tratamiento-y-manejo-de-la-enfermedad-de-alzheimer\/?lang=es\">\n\t\t\t\t\t\t\t<div class=\"elementor-cta__content\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-content-item elementor-cta__content-item elementor-cta__image\">\n\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"500\" height=\"396\" src=\"https:\/\/detectalz.com\/wp-content\/uploads\/2024\/03\/Treating-and-Managing-Alzheimers.gif\" class=\"attachment-full size-full wp-image-210347\" alt=\"\" \/>\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t<h2 class=\"elementor-cta__title elementor-cta__content-item elementor-content-item\">\n\t\t\t\t\t\tTratamiento y Manejo del Alzheimer\t\t\t\t\t<\/h2>\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-e7823cf elementor-hidden-mobile elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"e7823cf\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-wide\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-inner-column elementor-element elementor-element-428f9b5\" data-id=\"428f9b5\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-9b17ecf elementor-cta--layout-image-above elementor-cta--valign-middle toolkit-box elementor-cta--skin-classic elementor-animated-content elementor-widget elementor-widget-call-to-action\" data-id=\"9b17ecf\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"call-to-action.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<a class=\"elementor-cta\" href=\"https:\/\/detectalz.com\/clinical-toolkit\/ad-rapid-referral\/\">\n\t\t\t\t\t\t\t<div class=\"elementor-cta__content\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-content-item elementor-cta__content-item elementor-cta__image\">\n\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"500\" height=\"396\" src=\"https:\/\/detectalz.com\/wp-content\/uploads\/2024\/03\/AD-Rapid-Referral.gif\" class=\"attachment-full size-full wp-image-210349\" alt=\"\" \/>\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t<h2 class=\"elementor-cta__title elementor-cta__content-item elementor-content-item\">\n\t\t\t\t\t\tDerivaci\u00f3n r\u00e1pida de la AD\t\t\t\t\t<\/h2>\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-inner-column elementor-element elementor-element-57e519b\" data-id=\"57e519b\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-78baf32 elementor-cta--layout-image-above elementor-cta--valign-middle toolkit-box elementor-cta--skin-classic elementor-animated-content elementor-widget elementor-widget-call-to-action\" data-id=\"78baf32\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"call-to-action.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<a class=\"elementor-cta\" href=\"https:\/\/detectalz.com\/intercambio-clinico\/?lang=es\">\n\t\t\t\t\t\t\t<div class=\"elementor-cta__content\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-content-item elementor-cta__content-item elementor-cta__image\">\n\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"500\" height=\"396\" src=\"https:\/\/detectalz.com\/wp-content\/uploads\/2024\/03\/Clinical-Exchange.gif\" class=\"attachment-full size-full wp-image-210351\" alt=\"\" \/>\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t<h2 class=\"elementor-cta__title elementor-cta__content-item elementor-content-item\">\n\t\t\t\t\t\tIntercambio cl\u00ednico\t\t\t\t\t<\/h2>\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-inner-column elementor-element elementor-element-0baa7b9\" data-id=\"0baa7b9\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-cc0cc70 elementor-cta--layout-image-above elementor-cta--valign-middle toolkit-box elementor-cta--skin-classic elementor-animated-content elementor-widget elementor-widget-call-to-action\" data-id=\"cc0cc70\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"call-to-action.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<a class=\"elementor-cta\" href=\"https:\/\/detectalz.com\/recursos-adicionales\/?lang=es\">\n\t\t\t\t\t\t\t<div class=\"elementor-cta__content\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-content-item elementor-cta__content-item elementor-cta__image\">\n\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"500\" height=\"396\" src=\"https:\/\/detectalz.com\/wp-content\/uploads\/2024\/03\/Additional-Resources.gif\" class=\"attachment-full size-full wp-image-210353\" alt=\"\" \/>\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t<h2 class=\"elementor-cta__title elementor-cta__content-item elementor-content-item\">\n\t\t\t\t\t\tRecursos adicionales\t\t\t\t\t<\/h2>\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-1cce568 elementor-hidden-desktop elementor-hidden-tablet elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"1cce568\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-wide\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-16 elementor-inner-column elementor-element elementor-element-d4282e9\" data-id=\"d4282e9\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-0da3280 elementor-cta--layout-image-above elementor-cta--valign-middle toolkit-box elementor-cta--skin-classic elementor-animated-content elementor-widget elementor-widget-call-to-action\" data-id=\"0da3280\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"call-to-action.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<a class=\"elementor-cta\" href=\"https:\/\/detectalz.com\/el-peso-de-la-enfermedad-de-alzheimer\/?lang=es\">\n\t\t\t\t\t\t\t<div class=\"elementor-cta__content\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-content-item elementor-cta__content-item elementor-cta__image\">\n\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"500\" height=\"403\" src=\"https:\/\/detectalz.com\/wp-content\/uploads\/2024\/03\/The-Burden-of-AD.gif\" class=\"attachment-full size-full wp-image-210343\" alt=\"\" \/>\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t<h2 class=\"elementor-cta__title elementor-cta__content-item elementor-content-item\">\n\t\t\t\t\t\tEl peso de la enfermedad de Alzheimer\t\t\t\t\t<\/h2>\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-16 elementor-inner-column elementor-element elementor-element-523974e\" data-id=\"523974e\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-af059bb elementor-cta--layout-image-above elementor-cta--valign-middle toolkit-box elementor-cta--skin-classic elementor-animated-content elementor-widget elementor-widget-call-to-action\" data-id=\"af059bb\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"call-to-action.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<a class=\"elementor-cta\" href=\"https:\/\/detectalz.com\/diagnostico-y-evaluacion-de-la-enfermedad-de-alzheimer\/?lang=es\">\n\t\t\t\t\t\t\t<div class=\"elementor-cta__content\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-content-item elementor-cta__content-item elementor-cta__image\">\n\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"500\" height=\"396\" src=\"https:\/\/detectalz.com\/wp-content\/uploads\/2024\/03\/Diagnosis-and-Assessing-AD.gif\" class=\"attachment-full size-full wp-image-210345\" alt=\"\" \/>\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t<h2 class=\"elementor-cta__title elementor-cta__content-item elementor-content-item\">\n\t\t\t\t\t\tDiagn\u00f3stico y evaluaci\u00f3n de la enfermedad de Alzheimer\t\t\t\t\t<\/h2>\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-16 elementor-inner-column elementor-element elementor-element-36a10c3\" data-id=\"36a10c3\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-aefff16 elementor-cta--layout-image-above elementor-cta--valign-middle toolkit-box elementor-cta--skin-classic elementor-animated-content elementor-widget elementor-widget-call-to-action\" data-id=\"aefff16\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"call-to-action.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<a class=\"elementor-cta\" href=\"https:\/\/detectalz.com\/tratamiento-y-manejo-de-la-enfermedad-de-alzheimer\/?lang=es\">\n\t\t\t\t\t\t\t<div class=\"elementor-cta__content\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-content-item elementor-cta__content-item elementor-cta__image\">\n\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"500\" height=\"396\" src=\"https:\/\/detectalz.com\/wp-content\/uploads\/2024\/03\/Treating-and-Managing-Alzheimers.gif\" class=\"attachment-full size-full wp-image-210347\" alt=\"\" \/>\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t<h2 class=\"elementor-cta__title elementor-cta__content-item elementor-content-item\">\n\t\t\t\t\t\tTratamiento y manejo de la Enfermedad de Alzheimer\t\t\t\t\t<\/h2>\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-16 elementor-inner-column elementor-element elementor-element-7dcad5c\" data-id=\"7dcad5c\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-1c48ea9 elementor-cta--layout-image-above elementor-cta--valign-middle toolkit-box elementor-cta--skin-classic elementor-animated-content elementor-widget elementor-widget-call-to-action\" data-id=\"1c48ea9\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"call-to-action.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<a class=\"elementor-cta\" href=\"https:\/\/detectalz.com\/clinical-toolkit\/ad-rapid-referral\/\">\n\t\t\t\t\t\t\t<div class=\"elementor-cta__content\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-content-item elementor-cta__content-item elementor-cta__image\">\n\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"500\" height=\"396\" src=\"https:\/\/detectalz.com\/wp-content\/uploads\/2024\/03\/AD-Rapid-Referral.gif\" class=\"attachment-full size-full wp-image-210349\" alt=\"\" \/>\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t<h2 class=\"elementor-cta__title elementor-cta__content-item elementor-content-item\">\n\t\t\t\t\t\tDerivaci\u00f3n r\u00e1pida de la AD\t\t\t\t\t<\/h2>\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-16 elementor-inner-column elementor-element elementor-element-b4c5ecb\" data-id=\"b4c5ecb\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-7271692 elementor-cta--layout-image-above elementor-cta--valign-middle toolkit-box elementor-cta--skin-classic elementor-animated-content elementor-widget elementor-widget-call-to-action\" data-id=\"7271692\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"call-to-action.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<a class=\"elementor-cta\" href=\"https:\/\/detectalz.com\/intercambio-clinico\/?lang=es\">\n\t\t\t\t\t\t\t<div class=\"elementor-cta__content\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-content-item elementor-cta__content-item elementor-cta__image\">\n\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"500\" height=\"396\" src=\"https:\/\/detectalz.com\/wp-content\/uploads\/2024\/03\/Clinical-Exchange.gif\" class=\"attachment-full size-full wp-image-210351\" alt=\"\" \/>\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t<h2 class=\"elementor-cta__title elementor-cta__content-item elementor-content-item\">\n\t\t\t\t\t\tIntercambio cl\u00ednico\t\t\t\t\t<\/h2>\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-16 elementor-inner-column elementor-element elementor-element-8a54b7f\" data-id=\"8a54b7f\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-2a70191 elementor-cta--layout-image-above elementor-cta--valign-middle toolkit-box elementor-cta--skin-classic elementor-animated-content elementor-widget elementor-widget-call-to-action\" data-id=\"2a70191\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"call-to-action.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<a class=\"elementor-cta\" href=\"https:\/\/detectalz.com\/recursos-adicionales\/?lang=es\">\n\t\t\t\t\t\t\t<div class=\"elementor-cta__content\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-content-item elementor-cta__content-item elementor-cta__image\">\n\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"500\" height=\"396\" src=\"https:\/\/detectalz.com\/wp-content\/uploads\/2024\/03\/Additional-Resources.gif\" class=\"attachment-full size-full wp-image-210353\" alt=\"\" \/>\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t<h2 class=\"elementor-cta__title elementor-cta__content-item elementor-content-item\">\n\t\t\t\t\t\tRecursos adicionales\t\t\t\t\t<\/h2>\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>La enfermedad de Alzheimer (EA) es una afecci\u00f3n neurodegenerativa, caracterizada por la acumulaci\u00f3n de prote\u00edna beta-amiloide extraneuronal (placas) y prote\u00edna tau intraneuronal (ovillos) en el cerebro.1 Las etapas de la EA se clasifican por el grado de deterioro cognitivo, que va desde ning\u00fan s\u00edntoma de EA en la forma precl\u00ednica hasta s\u00edntomas graves en etapas [&hellip;]<\/p>\n","protected":false},"author":6,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"elementor_header_footer","meta":{"_acf_changed":false,"inline_featured_image":false,"site-sidebar-layout":"no-sidebar","site-content-layout":"page-builder","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"disabled","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center 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